Enzyme:2.1.2.8

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC2.-.-.- Transferases. : EC2.1.-.- Transferring one-carbon groups. : EC2.1.2.- Hydroxymethyl-, formyl- and related transferases.

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.1.2.8

5,10-methylenetetrahydrofolate:deoxycytidylate5-hydroxymethyltransferase
Systematic Name	5,10-methylenetetrahydrofolate:deoxycytidylate5-hydroxymethyltransferase
Common Name	deoxycytidylate 5-hydroxymethyltransferase dCMP hydroxymethylase d-cytidine 5'-monophosphate hydroxymethylase deoxyCMP hydroxymethylase deoxycytidylate hydroxymethylase

5,10-Methylene-tetrahydro-folic acid + dCMP + H2O => L-Tetrahydro-folic acid + 2'-Deoxy-5-hydroxy-methylcytidine 5'-phosphate (links: 5,10-Methylene-tetrahydro-folic acid + dCMP = L-Tetrahydro-folic acid + [(2R,3S,5R) -5- [4-Amino-5- (hydroxymethyl) -2-oxopyrimidin-1-yl] -3-hydroxyoxolan-2-yl] methyl dihydrogen phosphate)

5,10-Methylene-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFO0013$BMCCPTFOs005$0 L-Tetrahydro-folic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 14 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 15 ↔ 14 20 ↔ 15 19 ↔ 16 18 ↔ 17 17 ↔ 18 16 ↔ 19 21 ↔ 20 22 ↔ 21 23 ↔ 22 24 ↔ 23 25 ↔ 24 26 ↔ 25 27 ↔ 26 dCMP <Mapping> AtomMap:BMMCPYCT0021$BMMCPYCTq002$0 [(2R,3S,5R) -5- [4-Amino-5- (hydroxymethyl) -2-oxopyrimidin-1-yl] -3-hydroxyoxolan-2-yl] methyl dihydrogen phosphate 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 8 ↔ 8 9 ↔ 11 10 ↔ 12 11 ↔ 13 12 ↔ 14 13 ↔ 15 5,10-Methylene-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOs005$BMMCPYCTq002$0 [(2R,3S,5R) -5- [4-Amino-5- (hydroxymethyl) -2-oxopyrimidin-1-yl] -3-hydroxyoxolan-2-yl] methyl dihydrogen phosphate 9 ↔ 9