Enzyme:1.5.1.9

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.5.-.- Acting on the CH-NH group of donors. : EC1.5.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.5.1.9

N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase(L-glutamate-forming)
Systematic Name	N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase(L-glutamate-forming)
Common Name	saccharopine dehydrogenase (NAD+, L-glutamate-forming) dehydrogenase, saccharopine (nicotinamide adenine dinucleotide,glutamate-forming) saccharopin dehydrogenase NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde andglutamate forming) aminoadipic semialdehyde synthase (lysine-ketoglutarate reductase(EC 1. 5.1.8) and saccharopine dehydrogenase activity (EC 1.5.1.9)occur on a single protein, called aminoadipic semialdehydesynthase)

NAD+ + L-Saccharopine + H2O = NADH + L-2-Amino-adipate 6-semialdehyde + L-Glutamic acid (links: NAD+ + (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid = NADH + (2S) -2-Amino-6-oxohexanoic acid + (2S) -2-Amino-pentanedioic acid)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid <Mapping> AtomMap:BMAXS6ANk004$BMFYS6SAm006$0 (2S) -2-Amino-6-oxohexanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid <Mapping> AtomMap:BMAXS6ANk004$BMAAS5CA0007$0 (2S) -2-Amino-pentanedioic acid 8 ↔ 6 9 ↔ 2 10 ↔ 3 11 ↔ 4 12 ↔ 5 13 ↔ 1