Enzyme:2.1.2.11

Upper Levels: EC2.-.-.- Transferases. : EC2.1.-.- Transferring one-carbon groups. : EC2.1.2.- Hydroxymethyl-, formyl- and related transferases.

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.1.2.11

5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoatehydroxymethyltransferase
Systematic Name	5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoatehydroxymethyltransferase
Common Name	3-methyl-2-oxobutanoate hydroxymethyltransferase alpha-ketoisovalerate hydroxymethyltransferase dehydropantoate hydroxymethyltransferase ketopantoate hydroxymethyltransferase oxopantoate hydroxymethyltransferase

5,10-Methylene-tetrahydro-folic acid + 3-Methyl-2-oxo-butanoic acid + H2O => L-Tetrahydro-folic acid + 2-Dehydro-pantoic acid (links: 5,10-Methylene-tetrahydro-folic acid + 3-Methyl-2-oxo-butanoic acid = L-Tetrahydro-folic acid + 4-Hydroxy- 3,3-dimethyl-2-oxobutanoic acid)

5,10-Methylene-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFO0013$BMCCPTFOs005$0 L-Tetrahydro-folic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 14 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 15 ↔ 14 20 ↔ 15 19 ↔ 16 18 ↔ 17 17 ↔ 18 16 ↔ 19 21 ↔ 20 22 ↔ 21 23 ↔ 22 24 ↔ 23 25 ↔ 24 26 ↔ 25 27 ↔ 26 3-Methyl-2-oxo-butanoic acid <Mapping> AtomMap:BMFYB4CAr010$BMFYB4CAr008$0 4-Hydroxy- 3,3-dimethyl-2-oxobutanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 6 5 ↔ 5 5,10-Methylene-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOs005$BMFYB4CAr008$0 4-Hydroxy- 3,3-dimethyl-2-oxobutanoic acid 9 ↔ 4