Doc:UGT

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UDP Glycosyltransferases (UGTs)

Biological function of sugar conjugation

  • Increased stability
    • Anthocyanins are stabilized by the glycosylation at the 3-OH position.
  • Increased water solubility.
    • Compartmentalization into vacuole of phytoanticipins, glucosinolates, cyanogenic dhurrin.
  • Hormonal regulation
    • Cytokinin (CK) riboside is the xylem transport form.
    • Inactivation of hormones such as auxin (IAA), abscisic acid (AGA), , brassinosteroid (BR), salicylic acid. (However, jasmonic acid activity is enhanced by conjugation of isoleucine.)
    • Antifungal activity and membrane destabilization of oat saponins by C-3 conjugation [1]
    • Germination inhibition by piceid (glucoside of resveratrol) of Venturia inaequalis into apples [2]
  • Others
    • Tobacco UGT TOGT regulates the level of scopoletin (phytoalexin) [3][4].

Family Description

Family 1 UGT contains so-called plant secondary product glycosyltransferase (PSPG) motif (44 amino acids). The highly conserved HCGWNS residues interact with the uracil moiety of UDP-glucose [5].

Species Family 1 UGT
Arabidopsis thaliana 120 (http://www.biobase.dk/P450)
Medicago truncatula 165

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