Enzyme:6.3.2.2

Upper Levels: EC6.-.-.- Ligases. : EC6.3.-.- Forming carbon-nitrogen bonds. : EC6.3.2.- Acid--D-amino-acid ligases (peptide synthases).

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.3.2.2

L-glutamate:L-cysteine gamma-ligase (ADP-forming)
Systematic Name	L-glutamate:L-cysteine gamma-ligase (ADP-forming)
Common Name	glutamate-cysteine ligase gamma-glutamylcysteine synthetase gamma-glutamylcysteinyl synthetase

ATP + L-Glutamic acid + L-Cysteine => ADP + 5-L-Glutamyl-cysteine + Orthophosphate (links: ATP + (2S) -2-Amino-pentanedioic acid + L-Cysteine = ADP + (2S) -2-Amino-5- [ [ (2R) -1-hydroxy-1-oxo-3-sulfanylpropan-2-yl] amino] -5-oxopentanoic acid)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0020$0 ADP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 (2S) -2-Amino-pentanedioic acid <Mapping> AtomMap:BMAAS5CA0007$BMAXDP--0002$0 (2S) -2-Amino-5- [ [ (2R) -1-hydroxy-1-oxo-3-sulfanylpropan-2-yl] amino] -5-oxopentanoic acid 1 ↔ 6 2 ↔ 7 3 ↔ 8 4 ↔ 9 5 ↔ 10 6 ↔ 11 L-Cysteine <Mapping> AtomMap:BMAAS3SF0003$BMAXDP--0002$2 (3rd) (2S) -2-Amino-5- [ [ (2R) -1-hydroxy-1-oxo-3-sulfanylpropan-2-yl] amino] -5-oxopentanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5