Enzyme:3.1.2.5

Upper Levels: EC3.-.-.- Hydrolases. : EC3.1.-.- Acting on ester bonds. : EC3.1.2.- Thiolester hydrolases.

IDs and Links
IUBMB	EC3
ExPaSy	NiceZyme 3.1.2.5

(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase
Systematic Name	(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase
Common Name	hydroxymethylglutaryl-CoA hydrolase beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase beta-hydroxy-beta-methylglutaryl coenzyme A deacylase hydroxymethylglutaryl coenzyme A hydrolase hydroxymethylglutaryl coenzyme A deacylase

(S)-3-Hydroxy-3-methyl-glutaryl-CoA + H2O = CoA + 3-Hydroxy-3-methyl-glutaric acid (links: CoA +  (S) -3-Hydroxy-3-methyl-glutaryl-CoA = (S) -3-Hydroxy-3-methyl-glutaryl-CoA + 3-Hydroxy-3-methylglutaric acid)

CoA <Mapping> AtomMap:BMCCPUAPf023$BMFYB5CAa008$0 (S) -3-Hydroxy-3-methyl-glutaryl-CoA 1 ↔ 11 2 ↔ 12 3 ↔ 13 4 ↔ 14 5 ↔ 15 6 ↔ 16 7 ↔ 17 8 ↔ 18 9 ↔ 19 10 ↔ 20 11 ↔ 21 12 ↔ 22 13 ↔ 23 14 ↔ 24 15 ↔ 25 32 ↔ 42 33 ↔ 43 34 ↔ 45 35 ↔ 44 36 ↔ 46 37 ↔ 47 38 ↔ 48 39 ↔ 49 40 ↔ 50 41 ↔ 51 42 ↔ 52 43 ↔ 53 44 ↔ 54 45 ↔ 55 (S) -3-Hydroxy-3-methyl-glutaryl-CoA <Mapping> AtomMap:BMFYB5CAa008$BMFYB5DAr006$0 3-Hydroxy-3-methylglutaric acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6