Enzyme:1.5.1.3

Revision as of 09:00, 2 February 2009

5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
Systematic Name	5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
Common Name	dihydrofolate reductase tetrahydrofolate dehydrogenase DHFR pteridine reductase:dihydrofolate reductase dihydrofolate reductase:thymidylate synthase

NADPH + Folic acid => NADP+ + 7,8-Dihydro-folic acid
(links: NADP+ + Folic acid = NADPH + 7,8-Dihydro-folic acid)

NADP+	<Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0	NADPH
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32

Folic acid	<Mapping> AtomMap:BMCCPTFO0012$BMCCPTFO0011$0	7,8-Dihydro-folic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 16 ↔ 16 17 ↔ 17 18 ↔ 18 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26

NADPH + 7,8-Dihydro-folic acid => NADP+ + L-Tetrahydro-folic acid
(links: NADP+ + 7,8-Dihydro-folic acid = NADPH + L-Tetrahydro-folic acid)

NADP+	<Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0	NADPH
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32

7,8-Dihydro-folic acid	<Mapping> AtomMap:BMCCPTFO0011$BMCCPTFO0013$0	L-Tetrahydro-folic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 16 ↔ 16 17 ↔ 17 18 ↔ 18 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26

NADPH + Folic acid => NADP+ + L-Tetrahydro-folic acid
(links: NADP+ + Folic acid = NADPH + L-Tetrahydro-folic acid)

NADP+	<Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0	NADPH
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32

Folic acid	<Mapping> AtomMap:BMCCPTFO0012$BMCCPTFO0013$0	L-Tetrahydro-folic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 16 ↔ 16 17 ↔ 17 18 ↔ 18 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26

@@ Line 3: / Line 3: @@
 |SysName=5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
 |names=&&dihydrofolate reductase&&tetrahydrofolate dehydrogenase&&DHFR&&pteridine reductase:dihydrofolate reductase&&dihydrofolate reductase:thymidylate synthase
+}}
+{{Enzyme/Reaction| reaction= NADPH + Folic acid => NADP+ + 7,8-Dihydro-folic acid
+| list=
+&& BMCCPUAPt033$BMCCPUAPt034$0
+&& BMCCPTFO0012$BMCCPTFO0011$0
+}}
+{{Enzyme/Reaction| reaction= NADPH + 7,8-Dihydro-folic acid => NADP+ + L-Tetrahydro-folic acid
+| list=
+&& BMCCPUAPt033$BMCCPUAPt034$0
+&& BMCCPTFO0011$BMCCPTFO0013$0
+}}
+{{Enzyme/Reaction| reaction= NADPH + Folic acid => NADP+ + L-Tetrahydro-folic acid
+| list=
+&& BMCCPUAPt033$BMCCPUAPt034$0
+&& BMCCPTFO0012$BMCCPTFO0013$0
 }}

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.5.1.3